Antibaby syringe stopped for the man

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According to a WHO study, antibiotic injection for men has initially failed

Scientists have been researching the anti-baby syringe for men for decades. However, the methods tested so far have always been too unsafe or too risky due to the impending side effects. A large-scale study by the World Health Organization (WHO) was last stopped in March, as around ten percent of the test subjects did not tolerate the testosterone injection.

The study of the effectiveness of the anti-baby syringe for men with 400 participants from eight countries, which had been running since 2009, had to be stopped in March because every tenth test subject suffered from significant side effects such as depression, acne or massive weight gain. Study director Professor Michael Zitzmann, an andrologist and endocrinologist at the Center for Reproductive Medicine at the University of Münster, explained that the anti-baby syringe "does not work in its current composition." Success with the anti-baby syringe has been reported, so far none of the preparations has reached the market.

Side effects of the anti-baby syringe are too serious
As part of the WHO study, the 400 test subjects were given an anti-baby syringe based on active substances already approved for the treatment of other complaints every eight weeks in order to avoid lengthy approval procedures. The testosterone injections have already been successfully tested in various smaller national studies and should finally prove their effectiveness in the WHO study that has been running since 2009. However, unexpectedly, there were often significant side effects, so that the investigation had to be stopped in March this year, study director Professor Michael Zitzmann told the news agency "dpa". The anti-baby syringe in its current composition does not work, according to the expert. The injection had achieved the desired effects in 90 percent of the men, but ten percent suffered from considerable side effects. "It's just too much," emphasized Professor Michael Zitzmann. According to the study director, older study participants in particular developed side effects such as acne, depression, significant weight gain and increased libido. The massive side effects were particularly surprising for the scientists, as the previous national studies had shown no corresponding signs.

The previous anti-baby syringe approach does not work
The 400 participants in the WHO study were between the ages of 18 and 45, lived in a solid partnership, and their partners agreed to the test. By administering the testosterone injections every eight weeks, the testes stopped producing the body's own testosterone and subsequent sperm cells were actually no longer produced, the scientists report. Nevertheless, "the expectations were not met," said the head of the study at the Halle site, where 43 men were involved in the WHO study. "Although nine out of ten men tolerated the injection in Halle, the overall proportion of intolerance is too high," emphasized Prof. Dr. Hermann Behre, Director of the Center for Reproductive Medicine and Andrology at the University Hospital Halle. The study was therefore discontinued and the test subjects are currently in the aftercare and recovery phase, explained the study director at the Halle site. The final report of the study will not be available until October, "but we can already assume that it will not work in this form," Hermann Behre continues.

Do you still have market opportunities for the anti-baby syringe?
The researchers' original optimism was significantly dampened by the end of the WHO study. Professor Zitzmann emphasized, "We have to start from scratch, the result is open." However, a timely market launch of the anti-baby syringe is not to be expected under any circumstances. Nevertheless, Hermann Behre still sees great opportunities for the anti-baby syringe. "We are closer to success than some believe," explained the study director at the Halle location. Behre relies on the pure testosterone injection instead of a combination of already known active ingredients. “In China, such a testosterone syringe has been successfully tested on over 1,000 men. The results have been available since 2009, ”emphasized Behre. The market potential is still there, with “the anti-baby injection for men should not replace or replace the pill for women”. Rather, the injection offers couples the opportunity to share responsibility for contraception. Even if other contraceptive methods are out of the question for health reasons, such an anti-baby syringe offers a good alternative, the expert explained.

Pharmaceutical industry skeptical about new contraceptives for men
In the pharmaceutical industry, however, the market opportunities of the anti-baby syringe for men appear to be viewed rather skeptically. The research project based on a hormone injection and an implant was discontinued immediately after Bayer AG took over Schering AG in 2007, and Friederike Lorenzen of today's Bayer HealthCare Pharmaceuticals at Bayer Pharma AG (Berlin) told the news agency "dpa": "There will be no market opportunities for this in the next ten to 15 years." The 43 pharmaceutical companies organized in the Association of Researching Pharmaceutical Manufacturers (Berlin) also say that they are not carrying out any further research on such a contraceptive for men. The premature end of the WHO study on the effects and risks of the antibiotic injection for men is likely to have further worsened the prospects for private-sector research in this area.

Natural contraceptive methods without side effects sought
Since all active ingredients previously considered to be an anti-baby syringe, like the birth control pill, represent a significant intervention in the hormonal balance, side effects can generally be expected. In previous studies, however, these were always so pronounced that a market launch of the anti-baby syringe was impossible. But the question arises anyway, of alternative contraceptive methods that do not cause comparable side effects. As an alternative based on naturopathy, which guarantees a relatively high level of contraception, the Mexican Wild Yam (in German: the Mexican wild yam), which already played an important role in the invention of the contraceptive pill, comes into consideration. Mexican Wild Yam has been used in the medicine of Mexican indigenous peoples for generations to treat a wide variety of symptoms but also for prevention. (fp)

Also read:
Despite the protest: the birth control pill is 50 years old
Prevention with pill and condom preferred
Pharmaceutical company stops Viagra for women
Menopause also affects men

Image: Thomas Meinert,

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